Cresp 40 Injection
Darbepoetin alfa (40mcg)
by Dr Reddy's Laboratories Ltd
vial of 1 ml Injection
About this medicine
Cresp 40 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells. Cresp 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional. Common side effects include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures). Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash. Before taking Cresp 40 Injection, tell your doctor if you have heart disease, high blood pressure, or have had a seizure or stroke. If you are pregnant or breastfeeding, or plan to become pregnant or breastfeed, consult your doctor to make sure it is safe for you.
Uses
- Treatment of Anemia due to chronic kidney disease
- Treatment of Anemia due to cancer chemotherapy
Benefits
In treatment of Anemia due to chronic kidney disease
Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Chronic kidney disease (CKD) refers to the loss of normal kidney function over a long span of time. CKD progresses gradually over a few years but may become permanent if left untreated. CKD can lead to anemia. Cresp 40 Injection can boost your levels of red blood cells and reduce the symptoms of anemia such as tiredness and weakness. Taking this injection improves the quality of life.
How it works
Cresp 40 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
How to use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Common side effects
- Abdominal pain
- High blood pressure
- Rash
- Injection site pain
- Breathlessness
- Cough
- Peripheral edema
- Procedural hypotension (low blood pressure)
- Convulsion
- Thromboembolism
Safety advice
- AlcoholCONSULT YOUR DOCTOR
- It is not known whether it is safe to consume alcohol with Cresp 40 Injection. Please consult your doctor.
- PregnancyCONSULT YOUR DOCTOR
- Cresp 40 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
- Breast feedingCONSULT YOUR DOCTOR
- Cresp 40 Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
- DrivingSAFE
- Cresp 40 Injection does not usually affect your ability to drive.
- KidneySAFE IF PRESCRIBED
- Cresp 40 Injection is safe to use in patients with kidney disease. No dose adjustment of Cresp 40 Injection is recommended.
- LiverCAUTION
- Cresp 40 Injection should be used with caution in patients with liver disease. Dose adjustment of Cresp 40 Injection may be needed. Please consult your doctor.
If you miss a dose
If you miss a dose of Cresp 40 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick facts
- Chemical Class
- Amino Acids, Peptides Analogues
- Habit Forming
- No
- Therapeutic Class
- Blood related
- Action Class
- Erythropoiesis-stimulating agent (ESA)
Frequently asked questions
How long does it take for Cresp 40 Injection to start working?
You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Cresp 40 Injection. If you have any other concerns, consult your doctor.
Is Cresp 40 Injection safe to use?
Cresp 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Cresp 40 Injection therapy. Follow all the directions strictly.
Other than PRCA, can there be other reasons for not responding to Cresp 40 Injection?
You may not respond to Cresp 40 Injection if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.
Can Cresp 40 Injection be used in children?
Yes, Cresp 40 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Cresp 40 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.
Can Cresp 40 Injection affect blood pressure?
Yes, Cresp 40 Injection can affect blood pressure. During initial therapy with Cresp 40 Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Cresp 40 Injection if the blood pressure remains uncontrolled.
Who should not take Cresp 40 Injection?
Individuals who have cancer but have not been prescribed Cresp 40 Injection by the doctor should not take it. Additionally, patients with uncontrolled hypertension (high blood pressure), patients with a history of anemia called pure red cell aplasia (PRCA) that starts after treatment with Cresp 40 Injection or other erythropoietin medicines, and patients with a history of serious allergic reaction to this medicine should not take this medicine.
Product details
- Manufacturer
- Dr Reddy's Laboratories Ltd
- Salt composition
- Darbepoetin alfa (40mcg)
- Pack
- vial of 1 ml Injection
- Dosage form
- Injection
- Storage
- Store in a refrigerator (2 - 8°C). Do not freeze.
Same salt, other brands
Therapeutically equivalent. Ask your doctor or our pharmacist before substituting.
Darbitop 40mcg Injection
Darbepoetin alfa (40mcg)
prefilled syringe of 1 Injection
Save ₹626.00
The content above is for information only and is not a substitute for professional medical advice, diagnosis or treatment. Always consult a registered medical practitioner before starting, stopping or changing any medicine.