Entacom Tablet

Entacom Tablet is used in the treatment of Parkinson's disease. It helps to treat wearing-off symptoms of Parkinson's disease, such as stiffness, tremors, muscle spasms, and poor muscle control. Entacom Tablet is usually used in combination with carbidopa/levodopa. It may be taken with or without food, preferably at bedtime. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. This medication mustn't be stopped suddenly without talking to the doctor as it may worsen your condition. Your doctor may advise for periodic skin examination as it can cause melanoma. Some common side effects of this medicine include nausea, vomiting, fatigue, confusion, constipation, insomnia (difficulty sleeping), nightmares, and increased sweating. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is common to have diarrhea with this medicine, so drink plenty of fluids and watch for weight loss. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, and hallucinations. It may cause your urine to change in a brownish-orange color but it is not harmful and usually resolves once treatment is completed. Please consult your doctor if these side effects worry you or do not go away.

• Parkinson's disease

Entacom Tablet is a selective reversible inhibitor that is given in combination with levodopa. It works by inhibiting a chemical messenger [catechol-O-methyl transferase (COMT)] which in turn helps in increasing the amount of dopamine (chemical messenger) in the brain. Thus, an adequate amount of dopamine in the brain helps to coordinate body movements.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Entacom Tablet may be taken with or without food, but it is better to take it at a fixed time.

• Nausea
• Vomiting
• Fatigue
• Confusion
• Constipation
• Insomnia (difficulty in sleeping)
• Nightmares
• Hallucination
• Dizziness
• Diarrhea
• Muscle coordination impaired
• Abdominal pain
• Dryness in mouth

AlcoholUNSAFE

Entacom Tablet may cause excessive drowsiness with alcohol.

PregnancyCONSULT YOUR DOCTOR

Entacom Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feedingCONSULT YOUR DOCTOR

Entacom Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

DrivingCAUTION

Entacom Tablet may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.

KidneySAFE IF PRESCRIBED

Entacom Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Entacom Tablet may not be needed in these patients. Please consult your doctor.

LiverUNSAFE

Entacom Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

If you miss a dose of Entacom Tablet, skip it and continue with your normal schedule. Do not double the dose.

Chemical Class

Hydroxycinnamic Acids Derivatives

Habit Forming

No

Therapeutic Class

Neuro cns