Equirab 1500 Injection
Equine Rabies Immunoglobulin (1500IU)
by Bharat Serums & Vaccines Ltd
vial of 5 ml Injection
About this medicine
Equirab 1500 Injection is derived from the blood of horses. It neutralizes the virus at the wound site within a few hours. There are two types of Rabies Immunoglobulin (RIG), human (hRIG) and equine (eRIG). Both have similar clinical effectiveness in eliminating the virus at the wound site. Equirab 1500 Injection is given as an injection by a doctor or nurse. It is indicated in individuals with category III exposures (in-depth injury). RIG neutralizes the rabies virus at the inoculation site before the immune system responds to the vaccine by the production of rabies virus-neutralizing antibodies. Both active (vaccine) and passive immunization (Immunoglobulin) prevent the rabies virus from infiltrating the central nervous system, but become ineffective once the virus has crossed into the central nervous system. Equirab 1500 Injection is administered only once in a lifetime. The most common side effects include nausea, rash, and stomach upset. They do not normally last very long. Sitting or lying down can sometimes help. Consult your doctor if any of the side effects persist or worry you. Before having the injection, you should tell your doctor if you have ever had an allergic reaction to an immunoglobulin. Some other medicines may react with the equine rabies immunoglobulin so talk to your doctor about other medications you are taking as well. You should consult your doctor first if you are pregnant or breastfeeding.
Uses
- Prevention of Rabies
Benefits
In prevention of Rabies
Rabies is a serious disease caused by the rabies virus that is transmitted through the saliva of infected animals. Equirab 1500 Injection is given along with a rabies vaccine to prevent infection caused by the rabies virus to individuals with suspected rabies exposure. It works by neutralizing the virus at the wound site within a few hours before the immune system responds to the vaccine. It is to be administered only by or under the supervision of your doctor. You should not self administer this medicine.
How it works
Equirab 1500 Injection is an inactivated vaccine (made from a dead virus). It helps develop immunity by forming antibodies, which are proteins that protect against infection caused by viruses present in the vaccine.
How to use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Common side effects
- Nausea
- Rash
- Upset stomach
Safety advice
- AlcoholCONSULT YOUR DOCTOR
- It is not known whether it is safe to consume alcohol with Equirab 1500 Injection. Please consult your doctor.
- PregnancyCONSULT YOUR DOCTOR
- Information regarding the use of Equirab 1500 Injection during pregnancy is not available. Please consult your doctor.
- Breast feedingCONSULT YOUR DOCTOR
- Information regarding the use of Equirab 1500 Injection during breastfeeding is not available. Please consult your doctor.
- DrivingCONSULT YOUR DOCTOR
- It is not known whether Equirab 1500 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
- KidneySAFE IF PRESCRIBED
- Equirab 1500 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Equirab 1500 Injection may not be needed in these patients. Please consult your doctor.
- LiverSAFE IF PRESCRIBED
- Equirab 1500 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Equirab 1500 Injection may not be needed in these patients. Please consult your doctor.
If you miss a dose
If you miss a dose of Equirab 1500 Injection, please consult your doctor.
Quick facts
- Chemical Class
- Vaccines
- Habit Forming
- No
- Therapeutic Class
- Vaccines
Frequently asked questions
Is Equirab 1500 Injection better than human rabies immunoglobulin?
Equirab 1500 Injection is more economical as compared to human rabies immunoglobulin (HRIG) and hence more affordable to patients in developing countries, like India. However, Equirab 1500 Injection may cause anaphylaxis (a severe, potentially life-threatening allergic reaction), serum sickness and other allergic reactions and thus, physicians are hesitant to use it.
How effective is Equirab 1500 Injection?
Rabies is a 100% preventable disease. Proper wound management and simultaneous administration of Equirab 1500 Injection combined with anti-rabies vaccine (ARV) is almost invariably effective in preventing rabies, even after high-risk exposure.
Is Equirab 1500 Injection necessary?
Equirab 1500 Injection is not required for patients who have previously received a complete vaccination series of rabies.
How do you administer Equirab 1500 Injection ?
Equirab 1500 Injection should be administered into the muscle (the intramuscularly). If a large volume (> 2mL for children or > 5 mL for adults) is required, it is advised to divide the doses and for each dose a different site should be used. The immunoglobulin and the anti-rabies vaccine should be administered at two different sites of the body.
Is Equirab 1500 Injection painful?
Whether Equirab 1500 Injection is painful or not depends on your pain tolerance. During your initial treatment, a healthcare professional will put Equirab 1500 Injection in the area where you were bitten which can be painful. Therefore, you may need a relatively greater amount of Equirab 1500 Injection may be required to be placed in and around the wound site to ease out your pain and treat infection.
Product details
- Manufacturer
- Bharat Serums & Vaccines Ltd
- Salt composition
- Equine Rabies Immunoglobulin (1500IU)
- Pack
- vial of 5 ml Injection
- Dosage form
- Injection
- Storage
- Store in a refrigerator (2 - 8°C). Do not freeze.
The content above is for information only and is not a substitute for professional medical advice, diagnosis or treatment. Always consult a registered medical practitioner before starting, stopping or changing any medicine.