Imat 400 Tablet

Imat 400 Tablet is used to treat several types of cancers. It is most commonly prescribed to treat blood cancers (chronic myeloid leukemia and acute lymphocytic leukemia) and gastrointestinal stromal tumors. It works by targeting specific proteins that contribute to the growth and spread of cancer cells. Imat 400 Tablet is also used for treatment of a skin tumor called dermatofibrosarcoma protuberans and a type of bone marrow condition called aggressive systemic mastocytosis. The medicine should be taken with food. Take it at the same time each day to get the most benefit. Continue taking it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

• Treatment of Cancer

Imat 400 Tablet is an anti-cancer medication. A protein enzyme, bcr-abl tyrosine kinase, responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in bcr-abl positive cells (cancer cells). This is how it works to stop or slow the spread of cancer.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Imat 400 Tablet is to be taken with food.

• Edema (swelling)
• Nausea
• Vomiting
• Muscle cramp
• Musculoskeletal (bone, muscle or joint) pain
• Diarrhea
• Rash
• Fatigue
• Abdominal pain
• Bleeding
• Breathing problems
• Cough
• Weight gain
• Dry eye
• Dizziness
• Hemorrhage

AlcoholCONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Imat 400 Tablet. Please consult your doctor.

PregnancyCONSULT YOUR DOCTOR

Imat 400 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feedingCONSULT YOUR DOCTOR

Imat 400 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Lactating women should not breastfeed while using this drug and 15 days after stopping it.

DrivingUNSAFE

Imat 400 Tablet may cause side effects which could affect your ability to drive.

KidneyCAUTION

Imat 400 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Imat 400 Tablet may be needed. Please consult your doctor.

LiverCAUTION

Imat 400 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Imat 400 Tablet may be needed. Please consult your doctor.

If you miss a dose of Imat 400 Tablet, skip it and continue with your normal schedule. Do not double the dose.

Chemical Class

Benzanilides Derivative

Habit Forming

No

Therapeutic Class

Anti neoplastics

Action Class

Tyrosine kinase inhibitors