
Lyvelsa 20mg Tablet
Finerenone (20mg)
by Sun Pharmaceutical Industries Ltd
strip of 14 tablets
About this medicine
Lyvelsa 20mg Tablet is medicine used in the treatment of chronic kidney disease (CKD) caused by type 2 diabetes (T2D). It works by blocking a certain hormone in the body, which can help prevent the kidneys from getting worse and reduce the risk of heart-related issues like heart attacks and heart failure. Lyvelsa 20mg Tablet may be taken with or without food. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your blood pressure, heart rate, electrocardiogram (ECG), estimated glomerular filtration rate (eGFR), urine albumin‐to‐creatinine ratio (UACR), and potassium level till you become stable. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Common side effects of this medicine include high potassium level, low blood pressure, and low sodium level in the body. If you experience any of these side effects, consult your doctor. They may be able to help by reducing the dosage, or by prescribing you an alternate medicine. This medicine may not be suitable for everybody. Let your doctor know if you are suffering from any kidney or liver disease. Let your doctor also know about all the other medicines you are taking for any medical conditions. Pregnant and breastfeeding women should consult their doctors before taking this medicine.
Uses
- Treatment of Chronic kidney disease
Benefits
In treatment of Chronic kidney disease
Lyvelsa 20mg Tablet is beneficial in reducing the risk of various complications in adults with chronic kidney disease (CKD) linked to type 2 diabetes (T2D). It helps prevent sustained decline in kidney function, progression to end-stage kidney disease, and cardiovascular-related events such as heart attack and heart failure. Additionally, Lyvelsa 20mg Tablet reduces the likelihood of hospitalization due to heart failure and lowers the risk of cardiovascular death. This way it helps manage CKD in diabetic patients, potentially improving both kidney and heart health outcomes.
How it works
Lyvelsa 20mg Tablet is a nonsteroidal, selective antagonist of the mineralocorticoid receptor (MR). This receptor, usually activated by hormones like aldosterone and cortisol, helps in controlling sodium levels in the body. Lyvelsa 20mg Tablet blocks and prevent this receptor from overactivation, which can damage different parts of the body such as the kidneys, heart, and blood vessels.
How to use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lyvelsa 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Common side effects
- Increased potassium level in blood
- Hypotension (low blood pressure)
- Decreased sodium level in blood
Safety advice
- AlcoholCONSULT YOUR DOCTOR
- It is not known whether it is safe to consume alcohol with Lyvelsa 20mg Tablet. Please consult your doctor.
- PregnancyCONSULT YOUR DOCTOR
- Lyvelsa 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
- Breast feedingCAUTION
- Lyvelsa 20mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
- DrivingCONSULT YOUR DOCTOR
- It is not known whether Lyvelsa 20mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
- KidneySAFE IF PRESCRIBED
- Lyvelsa 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Lyvelsa 20mg Tablet is recommended.
- LiverSAFE IF PRESCRIBED
- Lyvelsa 20mg Tablet is safe to use in patients with liver disease. No dose adjustment of Lyvelsa 20mg Tablet is recommended.
If you miss a dose
If you miss a dose of Lyvelsa 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick facts
- Habit Forming
- No
- Therapeutic Class
- Cardiac
Frequently asked questions
Can a breastfeeding women take Lyvelsa 20mg Tablet?
Breastfeeding women should exercised cautions while on treatment with this medicine. Consult your doctor.
Does Lyvelsa 20mg Tablet reduce the risk for heart failure events in high-risk patients?
Yes, a study reported that Lyvelsa 20mg Tablet reduces new-onset of heart failure and improves other heart failure outcomes in patients with chronic kidney disease and type 2 diabetes, irrespective of a history of heart failure or heart disease.
Does Lyvelsa 20mg Tablet increase potassium levels in the body?
Yes, Lyvelsa 20mg Tablet may result in hyperkalemia (increased potassium level), especially in patients with reduced kidney function and with already high potassium levels. Your doctor may monitor your potassium level before and during the treatment with Lyvelsa 20mg Tablet and may adjust its dose accordingly.
What is the dosing frequency of Lyvelsa 20mg Tablet?
Dosing of Lyvelsa 20mg Tablet is based on estimated glomerular filtration rate (eGFR). eGFR is the amount of waste, in milliliters, your kidneys should be able to filter in a minute. The initial dose of Lyvelsa 20mg Tablet is 20 mg daily for eGFR of ≥ 60 mL/min and 10 mg daily for eGFR of ≥ 25 to < 60 mL/minute. This medicine is not recommended for patients with eGFR < 25 mL/min. Your doctor may also adjust the dose if you have a high potassium level.
Can a breastfeeding women take Lyvelsa 20mg Tablet?
Breastfeeding is not recommended during treatment with this medicine and for 1 day after the treatment.
Can Lyvelsa 20mg Tablet result in low blood pressure?
Yes, Lyvelsa 20mg Tablet may cause a decrease in blood pressure that can lead to hypotension.
Product details
- Manufacturer
- Sun Pharmaceutical Industries Ltd
- Salt composition
- Finerenone (20mg)
- Pack
- strip of 14 tablets
- Dosage form
- Tablet
The content above is for information only and is not a substitute for professional medical advice, diagnosis or treatment. Always consult a registered medical practitioner before starting, stopping or changing any medicine.