P Zide 1000 Tablet

P Zide 1000 Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. P Zide 1000 Tablet is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects. Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain. You may also develop hepatitis (viral infection of the liver), increased liver enzymes and joint pain as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and might need dose modification. Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

• Tuberculosis (TB)

P Zide 1000 Tablet is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme), which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. P Zide 1000 Tablet may be taken with or without food, but it is better to take it at a fixed time.

• Jaundice
• Hepatitis (viral infection of liver)
• Increased liver enzymes
• Joint pain

AlcoholCAUTION

Caution is advised when consuming alcohol with P Zide 1000 Tablet. Please consult your doctor.

PregnancyCONSULT YOUR DOCTOR

P Zide 1000 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feedingSAFE IF PRESCRIBED

P Zide 1000 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

DrivingCONSULT YOUR DOCTOR

It is not known whether P Zide 1000 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

KidneyCAUTION

P Zide 1000 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of P Zide 1000 Tablet may be needed. Please consult your doctor. Kidney function tests are advised before you start taking this medicine.

LiverCAUTION

P Zide 1000 Tablet should be used with caution in patients with liver disease. Dose adjustment of P Zide 1000 Tablet may be needed. Please consult your doctor. Regular monitoring of liver function tests is advised before and after the start of the treatment.

If you miss a dose of P Zide 1000 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Chemical Class

Nicotinic acid derivatives

Habit Forming

No

Therapeutic Class

Anti infectives

Action Class

Mycobacterial fatty acid synthase