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Tilstigmin Tablet
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Tilstigmin Tablet

Neostigmine (15mg)

by Tablets India Limited

strip of 10 tablets

About this medicine

Tilstigmin Tablet is used in the treatment of myasthenia gravis (a disease-causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), postoperative urinary retention, and reversal of effect of skeletal muscle relaxants after surgery. Tilstigmin Tablet works by reducing and improving muscle weakness. It may be taken with or without food, preferably at the same time each day. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment. You should never stop this medicine suddenly without talking to your doctor. Some common side effects of using this medication are nausea, vomiting, abdominal cramps, increased production of saliva, and diarrhea. It usually does not cause dizziness and sleepiness. But, if you feel ill, avoid doing any such work that requires focus and attention, such as driving or operating any machinery. Before taking Tilstigmin Tablet, it is better to inform your doctor if you are suffering from any kidney problems, Parkinson's disease, asthma, or stomach disorders. Your blood pressure may decrease after taking this medicine, so it is better to monitor it and consult your doctor if it bothers you. This medicine may cause diarrhea, so drink plenty of fluids to keep yourself hydrated while taking this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding, before taking this medicine.

Uses

  • Myasthenia gravis
  • Paralytic ileus
  • Post-operative urinary retention
  • Reversal of effect of skeletal muscle relaxant after surgery

Benefits

In myasthenia gravis

Myasthenia gravis is a neuromuscular disorder that leads to weakness of muscles that are under our control, such as those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. It happens due to impaired coordination between muscles and nerves. Tilstigmin Tablet makes this coordination between nerves and muscles better and relieves the symptoms. As a result, your muscle strength is improved and you are able to lead a better life.

How it works

Tilstigmin Tablet is a reversible cholinesterase inhibitor. When taken by mouth it increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.

How to use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tilstigmin Tablet may be taken with or without food, but it is better to take it at a fixed time.

Common side effects

  • Nausea
  • Vomiting
  • Abdominal cramp
  • Diarrhea
  • Increased saliva production

Safety advice

AlcoholUNSAFE
Tilstigmin Tablet may cause excessive drowsiness with alcohol.
PregnancyCONSULT YOUR DOCTOR
Tilstigmin Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feedingSAFE IF PRESCRIBED
Tilstigmin Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
DrivingCONSULT YOUR DOCTOR
It is not known whether Tilstigmin Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
KidneyCAUTION
Tilstigmin Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tilstigmin Tablet may be needed. Please consult your doctor. Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.
LiverSAFE IF PRESCRIBED
Tilstigmin Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Tilstigmin Tablet may not be needed in these patients. Please consult your doctor.

If you miss a dose

If you miss a dose of Tilstigmin Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Quick facts

Chemical Class
Phenoxy Compounds
Habit Forming
No
Therapeutic Class
Neuro cns
Action Class
Cholinesterase inhibitors- carbamates

Frequently asked questions

Does Tilstigmin Tablet treat myasthenia gravis? How long do I need to take it?

Tilstigmin Tablet relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Tilstigmin Tablet will depend on your condition. Do not stop taking Tilstigmin Tablet until and unless advised by your doctor, even if you start feeling better.

How long does Tilstigmin Tablet take to start working?

Tilstigmin Tablet takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.

Is Tilstigmin Tablet a steroid?

No, Tilstigmin Tablet is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Tilstigmin Tablet work by preventing the breakdown of a chemical called acetylcholine.

Does it cause weight gain?

No, Tilstigmin Tablet does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.

Is Tilstigmin Tablet safe to use?

Yes, Tilstigmin Tablet is safe if used in the dose and duration prescribed by the doctor.

I felt better when I started taking Tilstigmin Tablet but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?

If your symptoms have started reappearing, then it could be due to increased severity of myasthenia gravis or excess dose of Tilstigmin Tablet. Both the conditions have similar effects, so it becomes very difficult to differentiate between the two. Do not increase the dose on your own and consult your doctor immediately.

Can I take Tilstigmin Tablet for constipation?

No, Tilstigmin Tablet should not be taken for any type of constipation. However, its use is limited to cases of constipation caused by paralysis of intestine and strictly on prescription by the doctor.

What should I do if I accidentally take more than the dose required?

You should seek immediate medical help in case of overdose of Tilstigmin Tablet.Excess of Tilstigmin Tablet may cause stomach pain, nausea, vomiting, diarrhea, blurred vision, difficulty in breathing, and excessive sweating, salivation, and weakness. It can even lead to paralysis.

Does Tilstigmin Tablet have any abuse potential?

No, there is no evidence of Tilstigmin Tablet having any abuse potential.

Who should not take Tilstigmin Tablet?

Tilstigmin Tablet should not be taken by patients who are allergic to it. Patients who are constipated or cannot urinate should avoid its use, unless advised by the doctor. This is because Tilstigmin Tablet is only used for certain types of urination problems and constipation (e.g. caused by paralysis of intestine).

Product details

Manufacturer
Tablets India Limited
Salt composition
Neostigmine (15mg)
Pack
strip of 10 tablets
Dosage form
Tablet
Storage
Store below 30°C

The content above is for information only and is not a substitute for professional medical advice, diagnosis or treatment. Always consult a registered medical practitioner before starting, stopping or changing any medicine.