
Tofatas Tablet
Tofacitinib (5mg)
by Intas Pharmaceuticals Ltd
strip of 14 tablets
About this medicine
Tofatas Tablet is used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. It helps decrease pain, tenderness, and swelling in the joints by reducing inflammation. It also helps slow the progression of bone and joint damage. Tofatas Tablet may be prescribed by itself or in combination with another medicine. The tablets can be taken with or without food and it is best to take them at the same time each day. Your dose will depend on your condition and what other medicines you are taking. You should use it as your doctor tells you to. Do not stop taking this medicine unless your doctor tells you to because your condition could get worse. The most common side effects of Tofatas Tablet include upper respiratory tract infections, headache, diarrhea, and nasopharyngitis. There are other less common side effects, some of them serious, including blood clots and tears in the stomach or intestine wall. These need urgent medical attention. If you have any worries about side effects, talk to your doctor. You may need blood tests before you are given this medicine and you should not start taking it if you have any kind of infection. Make sure you talk to your doctor before starting treatment if you have or have ever had, tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Tofatas Tablet can make you more likely to get infections or may worsen any current infections so avoid contact with people who have things you might catch (such as chickenpox, measles, flu). This medicine is not suitable for children under 18 years old and you should not use it if you are pregnant or breastfeeding, unless your doctor feels the benefit is greater than the risk. Your doctor may need to examine you regularly.
Uses
- Treatment of Rheumatoid arthritis
- Treatment of Psoriatic arthritis
- Treatment of Ankylosing spondylitis
- Treatment of Ulcerative colitis
Benefits
In treatment of Rheumatoid arthritis
Tofatas Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking the medicine even if you feel well because it is preventing future harm as well as improving your symptoms.
How it works
Tofatas Tablet is a Janus kinase inhibitor. It works by blocking the action of the enzyme, Janus kinase. This decreases the activity of the immune system and inflammation associated with rheumatic diseases and ulcerative colitis.
How to use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tofatas Tablet may be taken with or without food, but it is better to take it at a fixed time.
Common side effects
- Upper respiratory tract infection
- Headache
- Diarrhea
- Nasopharyngitis (inflammation of the throat and nasal passages)
Safety advice
- AlcoholSAFE
- Consuming alcohol with Tofatas Tablet does not cause any harmful side effects.
- PregnancyCONSULT YOUR DOCTOR
- Tofatas Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
- Breast feedingCONSULT YOUR DOCTOR
- Tofatas Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
- DrivingSAFE
- Tofatas Tablet does not usually affect your ability to drive.
- KidneyCAUTION
- Tofatas Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Tofatas Tablet may be needed. Please consult your doctor.
- LiverCAUTION
- Tofatas Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Tofatas Tablet may be needed. Please consult your doctor.
If you miss a dose
If you miss a dose of Tofatas Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick facts
- Chemical Class
- Pyrrolo Pyrimidine Derivative
- Habit Forming
- No
- Therapeutic Class
- Pain analgesics
- Action Class
- Janus kinase inhibitors
Frequently asked questions
Can I take Tofatas Tablet if I have liver problems?
Inform your doctor if you have liver problems, before starting Tofatas Tablet. This is done because in some cases Tofatas Tablet may cause an increase in liver enzymes. Therefore, your liver function needs to be investigated before starting Tofatas Tablet. Although, Tofatas Tablet can be given to patients with mild to moderate liver function impairment, but should not be prescribed to patients with severe liver impairment.
Can Tofatas Tablet cause cancer?
Tofatas Tablet may increase the chances of developing the risk of certain cancers (lymphoma and other cancers including skin cancers) by affecting the working of the immune system. Hence, inform your doctor if you ever had or have any type of cancer.
What is Tofatas Tablet used for?
Tofatas Tablet is approved for use in people with moderate to severe rheumatoid arthritis. It is an inflammatory disease of the joints. It is used if previous therapy did not work well or did not suit the patient. However, it can also be used earlier in treatment if the person does not respond well to the prescribed drugs. It can be used alone or together with some other medicines, such as methotrexate.
How long does it take for Tofatas Tablet to start working?
Tofatas Tablet usually takes about 2 to 8 weeks before you start feeling better, and it can take 3 to 6 months to feel the maximum effect of this medication.
Do I need to get any investigations done before starting Tofatas Tablet?
You may need to get your blood tests done before you start Tofatas Tablet or while you are taking it. Blood tests are done in order to check if you have a low red blood cell count (anemia), low white blood cell count (neutropenia or lymphopenia), high blood fat (cholesterol) or high levels of liver enzymes. It also helps to ensure that treatment with Tofatas Tablet is not causing problems. In addition to this, your doctor may advise you to get tested for tuberculosis before starting Tofatas Tablet, as using Tofatas Tablet may make an existing infection worse.
Can Tofatas Tablet cause infections?
Tofatas Tablet is a medicine that affects your immune system. This may reduce your ability to fight infection and may increase the risk of getting a serious infection including tuberculosis. It may also include infections caused by severe fungal, bacterial or viral infections that spread through the body. In some cases, these infections can be life-threatening and may even cause death. Hence, it is advised to treat these infections in a hospital.
If I am already taking tocilizumab, can I take Tofatas Tablet?
No, you should not take tocilizumab along with Tofatas Tablet. Tofatas Tablet affects the immune system, so you should avoid taking it with any other immunity-affecting medicine. Taking both medicines together can further increase the risk of infection and may lead to further complications.
Product details
- Manufacturer
- Intas Pharmaceuticals Ltd
- Salt composition
- Tofacitinib (5mg)
- Pack
- strip of 14 tablets
- Dosage form
- Tablet
- Storage
- Store below 30°C
Same salt, other brands
Therapeutically equivalent. Ask your doctor or our pharmacist before substituting.
The content above is for information only and is not a substitute for professional medical advice, diagnosis or treatment. Always consult a registered medical practitioner before starting, stopping or changing any medicine.

