
Ulyses 450mg Tablet SR
Ursodeoxycholic Acid (450mg)
by Lupin Ltd
strip of 10 tablet sr
About this medicine
Ulyses 450mg Tablet SR is used to dissolve certain gallstones and prevent them from forming. It is also used to treat a type of liver disease called primary biliary cirrhosis. It helps break down the cholesterol that has converted into stones in your gallbladder thereby dissolving the stones. Ulyses 450mg Tablet SR should be swallowed whole after a meal and with a glass of milk or water. The dose will depend on what you are being treated for and your body weight. Take it regularly to get maximum benefit and keep taking it for as long as prescribed (several months or longer). Keep taking it even if your symptoms disappear. This medicine's most common side effects are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets these side effects. If you are worried about them, or they do not go away, let your doctor know. Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, you get frequent cramp-like pain in your upper abdomen, you have been coughing up blood or you have gained weight rapidly. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor all other medicines you are taking. Women should discontinue hormonal birth control pills as they can increase the production of gallstones. During the treatment, you may need ultrasound scans, or frequent blood tests to check your liver function.
Uses
- Treatment of Primary biliary cirrhosis
- Treatment of Gallbladder stones
Benefits
In treatment of Primary biliary cirrhosis
Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Ulyses 450mg Tablet SR is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, you will likely be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.
How it works
Ulyses 450mg Tablet SR is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.
How to use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ulyses 450mg Tablet SR is to be taken with food.
Common side effects
- Abdominal pain
- Diarrhea
- Hair loss
- Itching
- Nausea
- Rash
Safety advice
- AlcoholUNSAFE
- Ulyses 450mg Tablet SR may cause excessive drowsiness with alcohol.
- PregnancySAFE IF PRESCRIBED
- Ulyses 450mg Tablet SR is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
- Breast feedingSAFE IF PRESCRIBED
- Ulyses 450mg Tablet SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
- DrivingSAFE
- Ulyses 450mg Tablet SR does not usually affect your ability to drive.
- KidneyCONSULT YOUR DOCTOR
- There is limited information available on the use of Ulyses 450mg Tablet SR in patients with kidney disease. Please consult your doctor.
- LiverCONSULT YOUR DOCTOR
- There is limited information available on the use of Ulyses 450mg Tablet SR in patients with liver disease. Please consult your doctor.
If you miss a dose
If you miss a dose of Ulyses 450mg Tablet SR, skip it and continue with your normal schedule. Do not double the dose.\\n
Quick facts
- Chemical Class
- Bile Acids and Salts
- Habit Forming
- No
- Therapeutic Class
- Gastro intestinal
- Action Class
- Hepatoprotectives
Frequently asked questions
When should I take Ulyses 450mg Tablet SR?
The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Ulyses 450mg Tablet SR should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.
Is Ulyses 450mg Tablet SR safe?
Ulyses 450mg Tablet SR is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.
How does Ulyses 450mg Tablet SR help the liver?
Ulyses 450mg Tablet SR acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.
Does Ulyses 450mg Tablet SR cause weight gain?
Yes, there is a chance of weight gain with Ulyses 450mg Tablet SR, but it is not common. The use of Ulyses 450mg Tablet SR can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.
What should I avoid while taking Ulyses 450mg Tablet SR?
While taking Ulyses 450mg Tablet SR, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Ulyses 450mg Tablet SR. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Ulyses 450mg Tablet SR. So, ask your doctor about the time gap that should be maintained between Ulyses 450mg Tablet SR and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Ulyses 450mg Tablet SR.
Product details
- Manufacturer
- Lupin Ltd
- Salt composition
- Ursodeoxycholic Acid (450mg)
- Pack
- strip of 10 tablet sr
- Dosage form
- Tablet
- Storage
- Store below 30°C
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Therapeutically equivalent. Ask your doctor or our pharmacist before substituting.

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The content above is for information only and is not a substitute for professional medical advice, diagnosis or treatment. Always consult a registered medical practitioner before starting, stopping or changing any medicine.